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U-47700 is a structural isomer of the earlier opioid AH-7921 and the result of a great deal of work elucidating the quantitative structure–activity relationship of the scaffold. Upjohn looked for the key moieties which gave the greatest activity and posted over a dozen patents on related compounds, each optimizing one moiety until they discovered that U-47700 was the most active.
U-47700 became the lead compound of selective kappa-opioid receptor ligands such as U-50488, U-51754 (containing a single methylene spacer difference) and U-69,593, which share very similar structures. Although not used medically, the selective kappa ligands are used in research
What are the health effects/risks of using U-47700?
Many users of U-47700 are being sedated to the point they stop breathing.
If the overdose is not immediately fatal and there is someone available to call for help, first responders can employ
naloxene, an opiate antidote, in an effort to save a life. However, there are fears the effects of U-47700 are so strong
it could be resistant to naloxene, especially when multiple doses are not available.Unregulated drugs pose extreme danger as suppliers may practice inconsistent manufacturing practices. Each batch can have sizable variations in potency and makeup, putting users at high risk of a fatal overdose. Buy U-47700 Powder online without prescription.
How to keep the medecine?
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Store between 4 to 25 degrees C (40 to 72 degrees F
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